PROTAC SMARCA2/4-degrader-9

SKU T89170-10 mg Category Brand:

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Products Details

Product Description

– PROTAC SMARCA2/4-degrader-9 (Compound I-503) is a PROTAC degrader targeting the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. It effectively degrades SMARCA2 in MV411 and A549 cells, with a DC50 of less than 100 nM, and degrades SMARCA4 in MV411 with a similar DC50.

Web ID

– T89170

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C49H59N11O5S

CAS Number

– 2568507-15-1

Molecular Weight

– C49H59N11O5S

SMILES

– NC1=C(N2CC3N(C(C2)CC3)C=4N=CC(=CN4)C5CCC(C(N[C@H](C(=O)N6[C@H](C(NCC7=CC=C(C=C7)C8=C(C)N=CS8)=O)C[C@@H](O)C6)C(C)(C)C)=O)CC5)C=C(N=N1)C9=C(O)C=CC=C9

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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