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Products Details
Product Description
– PROTAC SMARCA2/4-degrader-8 (Compound I-502) is a PROTAC degrader targeting the catalytic subunit SMARCA of the SWI/SNF complex. It degrades SMARCA2 in A549 and MV411 cells with a DC50 of <100 nM and SMARCA4 in MV411 cells, also exhibiting a DC50 of <100 nM.
Web ID
– T88872
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C50H61N11O5S
CAS Number
– 2568507-14-0
Molecular Weight
– C50H61N11O5S
SMILES
– NC1=C(N2CC3N(C(C2)CC3)C=4N=CC(=CN4)C5CCC(CC(N[C@H](C(=O)N6[C@H](C(NCC7=CC=C(C=C7)C8=C(C)N=CS8)=O)C[C@@H](O)C6)C(C)(C)C)=O)CC5)C=C(N=N1)C9=C(O)C=CC=C9
Product type
– PROTAC
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