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Products Details
Product Description
– PROTAC SMARCA2/4-degrader-31 (Compound I-280) serves as a degrader for the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. It effectively degrades SMARCA2 in A549 cells and SMARCA4 in MV411 cells, both with a degradation concentration (DC50) of less than 100 nM.
Web ID
– T89934
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C44H51N11O4
CAS Number
– 2568273-83-4
Molecular Weight
– C44H51N11O4
SMILES
– O=C1N(C=2C(=CC(=CC2)[C@@H]3CC[C@H](CC3)N4CCC(CC4)C=5N=C(C=CN5)N6C7CN(CC6CC7)C=8C=C(N=NC8N)C9=C(O)C=CC=C9)N1C)C%10C(=O)NC(=O)CC%10
Pathway
– Chromatin/Epigenetic|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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