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Products Details
Product Description
– Compound I-291, also known as PROTAC SMARCA2/4-degrader-30, targets the catalytic subunits of the SWI/SNF complex, specifically SMARCA2 and SMARCA4. It effectively degrades SMARCA2 in A549 and MV411 cells, as well as SMARCA4 in MV411 cells, with a degradation concentration (DC50) of less than 100 nM.
Web ID
– T200023
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C44H51N11O4
CAS Number
– 2568276-44-6
Molecular Weight
– C44H51N11O4
SMILES
– NC1=C(N2CC3N(C(C2)CC3)C=4N=CC(=CN4)C5CCN(CC5)[C@@H]6CC[C@H](CC6)C=7C=C8C(=CC7)N(C(=O)N8C)C9C(=O)NC(=O)CC9)C=C(N=N1)C%10=C(O)C=CC=C%10
Target
– Others
Pathway
– Chromatin/Epigenetic|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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