Download Files:
Products Details
Product Description
– PROTAC SMARCA2/4-degrader-18 (Compound I-348) is a PROTAC degrader targeting the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. It effectively degrades SMARCA2 in A549 cells with a DC50 value of less than 100 nM and similarly degrades SMARCA4 in MV411 cells, also with a DC50 of less than 100 nM.
Web ID
– T89590
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C55H64N12O5S
CAS Number
– 2568276-91-3
Molecular Weight
– C55H64N12O5S
SMILES
– NC1=C(N2CC3N(C(C2)CC3)C=4N=CC(=CN4)C5CCN(CC6=CC=C(C(N[C@H](C(=O)N7[C@H](C(NCC8=CC=C(C=C8)C9=C(C)N=CS9)=O)C[C@@H](O)C7)[C@](C)(C)C)=O)C=C6)CC5)C=C(N=N1)C%10=C(O)C=CC=C%10
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
