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Products Details
Product Description
– PROTAC MPS1 degrader 1 (Compound 19) acts as a potent degrader of Monopolar spindle 1 (Mps1, TTK), AURKA, and AURKB, with DC50 values of 17.7, 108.7, and 570.3 nM respectively. It is utilized in the study of acute myeloid leukemia. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase)
Web ID
– T201080
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C41H46N12O7
Molecular Weight
– C41H46N12O7
SMILES
– O(C)C=1C=C2C(=CC1OC)CCN(CCC3=CC=C(/N=N/C4=C(NC(=O)C5=C(OC)C=CC=C5)C=CC=C4)C=C3)C2
Target
– Others
Pathway
– Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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