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Products Details
Product Description
– PROTAC MDM2 Degrader-2, designed using PROTAC technology, functions as a MDM2 degrader. It consists of a highly potent MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase, facilitating the degradation of MDM2[1].
Web ID
– T18632
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C70H76Cl4N10O12
References
– Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A.
CAS Number
– 2249944-99-6
Molecular Weight
– C70H76Cl4N10O12
SMILES
– COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCN(CC(=O)NCCOCCOCCNC(=O)CN3CCN(CC3=O)C(=O)N3[C@H]([C@H](N=C3c3ccc(OC)cc3OC(C)C)c3ccc(Cl)cc3)c3ccc(Cl)cc3)C(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
Target
– EGFR|||Drug Metabolite
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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