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Products Details
Product Description
– PROTAC LZK-IN-1 (Compound 21A) is a PROTAC molecule that targets the degradation of LZK (leucine zipper kinase, encoded by MAP3K13). At a concentration of 10 μM, PROTAC LZK-IN-1 facilitates the degradation of LZK and inhibits the expression of p53 and c-MYC, leading to reduced viability of global head and neck squamous cell carcinoma (HNSCC) cell lines. This compound is applicable in anticancer research.
Web ID
– T204373
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C51H64F2N10O5S
CAS Number
– 2763268-64-8
Molecular Weight
– C51H64F2N10O5S
SMILES
– C([C@@H](NC(CCCCCCC(=O)N1CCC(CC1)C=2C=C(N=C(NC3=CC(C#N)=CC=N3)C2)N4CCC(F)(F)C4)=O)C(C)(C)C)(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C7=C(C)N=CS7)=O)C[C@@H](O)C5
Pathway
– Apoptosis|||MAPK|||Cell Cycle/Checkpoint|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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