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Products Details
Product Description
– PROTAC HSP90 degrader BP3 potently and selectively degrades HSP90 through a CRBN-dependent mechanism. It effectively diminishes HSP90 protein levels in MCF-7 cells with a half-maximal degradation concentration (DC50) of 0.99 µM. Additionally, this compound impedes the proliferation of breast cancer cells [1].
Web ID
– T73835
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C32H29ClN8O5
CAS Number
– 2669072-88-0
Molecular Weight
– C32H29ClN8O5
SMILES
– COc1c(C)cnc(Cn2cc(C#CCCNc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)c3c(Cl)nc(N)nc23)c1C
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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