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Product Description
– PROTACFLT-3degrader 4 is an orally active CRBN-based FLT3-PROTAC degrader that efficiently induces the degradation of FLT3-ITD via the ubiquitin-proteasome system. It demonstrates high selectivity for FLT3-ITD mutant acute myeloid leukemia (AML) cells. [Blue: CRBN ligand, Black: linker; Pink: FLT3 inhibitor].
Web ID
– T87986
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C39H41FN8O6
CAS Number
– 2956722-48-6
Molecular Weight
– C39H41FN8O6
SMILES
– O=C1N(C(=O)C=2C1=CC(=CC2)N3CCC(CN4CCN(CC(NC=5C(C)=C(/C=C6/C=7C(NC6=O)=CC=C(F)C7)NC5)=O)CC4)CC3)C8C(=O)NC(=O)CC8
Product type
– PROTAC
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