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Products Details
Product Description
– PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD) with an IC50 of 0.6 nM and exhibits anti-proliferative activity.
Web ID
– T12555
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C52H61N9O9S2
References
– Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432.
CAS Number
– 2230826-81-8
Molecular Weight
– C52H61N9O9S2
SMILES
– O(CCOCCOCCC(N[C@H](C(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1)C(C)(C)C)=O)C=4C=C5C(N6C(S5)=NC(=C6)C7=CC=C(NC(NC=8C=C(C(C)(C)C)ON8)=O)C=C7)=CC4
Target
– LRRK2
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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