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Products Details
Product Description
– PROTAC EGFR Degrader 5 (Compound 10), a potent degrader of EGFR Del19 in HCC827 cells, achieves this with a DC50 of 34.8 nM. This compound effectively induces apoptosis in HCC827 cells and causes cell cycle arrest in the G1 phase [1].
Web ID
– T74524
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C57H72FN13O5S
CAS Number
– 2409793-36-6
Molecular Weight
– C57H72FN13O5S
SMILES
– Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN2CCN(CC2)c2ccc(Nc3cc4c(nc(Nc5ccc(F)cc5)nc4cn3)N3CCC(CO)CC3)nc2)C(C)(C)C)cc1
Pathway
– Others
Product type
– PROTAC
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