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PR-619
Price range: 72 CAD through 629 CAD
Products Details
Product Description
– PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor that inhibits USP2/4/5/7/8 (EC50=7.2/3.93/8.61/6.86/4.9 μM). PR-619 induces endoplasmic reticulum stress and activates autophagy.
Web ID
– T1862
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C7H5N5S2
Citations
– 1. Song P, Yang S, Hua H, et al. The regulatory protein GADD34 inhibits TRAIL-induced apoptosis via TRAF6/ERK-dependent stabilization of myeloid cell leukemia 1 in liver cancer cells. Journal of Biological Chemistry. 2019: jbc. RA118. 006029
References
– Altun M, et al. Chem Biol, 2011, 18(11), 1401-1412.
CAS Number
– 2645-32-1
Molecular Weight
– C7H5N5S2
Compound Purity
– 0.9983
SMILES
– Nc1nc(N)c(SC#N)cc1SC#N
Target
– Others
Pathway
– Autophagy|||Apoptosis|||Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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