PQCA
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PQCA

SKU T12531-1 mg Category Brand:

Price range: 75 CAD through 942 CAD

Products Details

Product Description

– PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and 135 nM in human M1 receptors, but showed no activity against other muscarinic receptors. PQCA is a potential compound for reducing cognitive deficits associated with Alzheimer’s disease.

Web ID

– T12531

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H20N4O3

References

– Lange HS, et al. The M1 Muscarinic Positive Allosteric Modulator PQCA Improves Performance on Translatable Tests of Memory and Attention in Rhesus Monkeys. J Pharmacol Exp Ther. 2015;355(3):442-450.

CAS Number

– 1144504-35-7

Molecular Weight

– C22H20N4O3

Compound Purity

– 0.9895

SMILES

– OC(=O)c1cc(CN2CCC(CC2)(C#N)c2ccccn2)c2ccccn2c1=O

Target

– Molecular Glues

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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