PP2
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PP2

SKU T6266-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 1,221 CAD

Products Details

Product Description

– PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.

Web ID

– T6266

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H16ClN5

Citations

– 1. Zheng T, Wang H Y, Chen Y, et al. Src Activation Aggravates Podocyte Injury in Diabetic Nephropathy via Suppression of FUNDC1-Mediated Mitophagy. Frontiers in Pharmacology. 2022, 13: 897046-897046 2. Liu K, Hao Z, Zheng H, et al.Repurposing of rilpivirine for preventing platelet β3 integrin-dependent thrombosis by targeting c-Src active autophosphorylation.Thrombosis Research.2023

References

– Hanke JH, et al. J Biol Chem, 1996, 271(2), 695-701.

CAS Number

– 172889-27-9

Molecular Weight

– C15H16ClN5

Compound Purity

– 0.98

SMILES

– NC1=C2C(=NN(C(C)(C)C)C2=NC=N1)C3=CC=C(Cl)C=C3

Pathway

– JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Stem Cells|||Angiogenesis|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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