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PNZ5
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1)[1].
Web ID
– HY-100696
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H18N2O2
References
– [1]Montenegro RC, et al. BET inhibition as a new strategy for the treatment of gastric cancer. Oncotarget. 2016 Jul 12;7(28):43997-44012.
CAS Number
– 1629277-36-6
Molecular Weight
– 318.37
SMILES
– CN1C(C2=CC=C(C3=C(C)ON=C3C)C=C2[C@@]1(C4=CC=CC=C4)[H])=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BRD4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
