PNZ5
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PNZ5

SKU T12513-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 187 CAD through 2,432 CAD

Products Details

Product Description

– PNZ5, an isoxazole-based pan-BET inhibitor, demonstrates potent activity and high selectivity comparable to the established (+)-JQ1, exhibiting a dissociation constant (KD) of 5.43 nM for BRD4(1).

Web ID

– T12513

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H18N2O2

References

– Montenegro RC, et al. BET inhibition as a new strategy for the treatment of gastric cancer. Oncotarget. 2016 Jul 12;7(28):43997-44012.

CAS Number

– 1629277-36-6

Molecular Weight

– C20H18N2O2

Compound Purity

– 1

SMILES

– CN1[C@H](C=2C(C1=O)=CC=C(C2)C=3C(C)=NOC3C)C4=CC=CC=C4

Target

– ERK|||MEK|||mTOR|||Apoptosis|||Akt

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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