Pimozide
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Pimozide

SKU T2546-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 78 CAD

Products Details

Product Description

– Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby decreasing dopamine neurotransmission and reducing the occurrence of the motor and vocal tics and delusions of parasitosis. In addition, this agent antagonizes alpha-adrenergic and 5-HT2 receptors.

Web ID

– T2546

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H29F2N3O

Citations

– 1. Wang Y, Wang X, Wang K, et al.Chronic stress accelerates glioblastoma progression via DRD2/ERK/β-catenin axis and Dopamine/ERK/TH positive feedback loop.Journal of Experimental & Clinical Cancer Research.2023, 42(1): 1-17.

References

– Silva MR, et al. Pharmacol Toxicol. 2003 Jul;93(1):42-7.

CAS Number

– 2062-78-4

Molecular Weight

– C28H29F2N3O

Compound Purity

– 0.9985

SMILES

– Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1

Pathway

– JAK/STAT signaling|||Stem Cells|||Membrane transporter/Ion channel|||GPCR/G Protein|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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