Pim-1 kinase inhibitor 3

SKU HY-150731-Get quote Category Tags , ,

Products Details

Product Description

– Pim-1 kinase inhibitor 3 (Compound H5) is a potent Pim-1 kinase inhibitor with an IC50 of 35.13 nM[1].

Web ID

– HY-150731

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C20H25N3O2

References

– [1]Xu J, et al. Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3-e][1,4]oxazine derivatives as novel Pim-1 kinase inhibitors. Bioorg Med Chem Lett. 2022 Sep 15;72:128874.

CAS Number

– 2801695-39-4

Molecular Weight

– 339.43

SMILES

– C12=CC3=C(C=C2)OC4=C(C=CN=C4)N3CCCCCNCCCCO1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Pim

Isoform

– PIM1

Pathway

– JAK/STAT Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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