Pifithrin-α
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Pifithrin-α, p-Nitro, Cyclic

SKU T12472-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 1,022 CAD

Products Details

Product Description

– Pifithrin-α, p-Nitro, Cyclic (PFN-α) is a cell-permeable, active-form inhibitor of p53.

Web ID

– T12472

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H13N3O2S

Citations

– 1. Mao C, Gong L, Kang W.Effect and mechanism of resveratrol on ferroptosis mediated by p53/SLC7A11 in oral squamous cell carcinoma.BMC Oral Health.2024, 24(1): 773. 2. Tang J, Liu W, Li Z, et al.Inhibition of ASIC1a reduces ferroptosis in rheumatoid arthritis articular chondrocytes via the p53/NRF2/SLC7A11 pathway.The FASEB Journal.2025, 39(1): e70298.

References

– Pietrancosta N, et al. Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism. J Med Chem. 2006 Jun 15;49(12):3645-52.

CAS Number

– 60477-38-5

Molecular Weight

– C15H13N3O2S

Compound Purity

– 0.9997

SMILES

– [O-][N+](=O)C1=CC=C(C=C1)C1=CN2C(SC3=C2CCCC3)=N1

Target

– 5-HT Receptor

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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