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Products Details
Product Description
– Se15 is a selective inhibitor of PI3Kδ with an IC50 value less than 0.1nM. Se15 can be used in research on autoimmune[1].
Web ID
– HY-157128
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H32N8O4Se
References
– [1]Li Gao, et al. Design, synthesis and bioactivity evaluation of selenium-containing PI3Kδ inhibitors. Bioorg Chem. 2023.
Molecular Weight
– 611.55
SMILES
– COC1=NC=C(C2=CC=C(N=CN=C3N[C@@H]4CN(C([C@@H](NC(OC(C)(C)C)=O)C[Se]C)=O)CC4)C3=N2)C=C1C#N
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PI3K
Isoform
– PI3Kδ
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
