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PF-573228
Price range: 72 CAD through 1,149 CAD
Products Details
Product Description
– PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.
Web ID
– T2001
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H20F3N5O3S
Citations
– 1. Wang W, Shen Z, Tang Y, et al. Astragaloside IV Promotes the Angiogenic Capacity of Adipose-derived Mesenchymal Stem Cells in a Hindlimb Ischemia Model by FAK Phosphorylation via CXCR2. Phytomedicine. 2021: 153908.
2. Wang W, Zhang D, Jiang Z, et al.A Nanodrug-Enabled chemosensitization of cancer stem cells against tumor progression and metastasis.Chemical Engineering Journal.2023, 477: 147121.
References
– Slack-Davis JK, et al. J Biol Chem, 2007, 282(20), 14845-14852.
CAS Number
– 869288-64-2
Molecular Weight
– C22H20F3N5O3S
Compound Purity
– 0.9886
SMILES
– CS(=O)(=O)c1cccc(CNc2nc(Nc3ccc4NC(=O)CCc4c3)ncc2C(F)(F)F)c1
Target
– Others
Pathway
– Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Angiogenesis|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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