PF-562271

SKU T2465-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 86 CAD through 1,336 CAD

Products Details

Product Description

– PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).

Web ID

– T2465

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H20F3N7O3S

Citations

– 1. Liu G, Jin X, Wang H, et al.Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer.Experimental Cell Research.2022: 113453.

References

– Roberts WG, et al. Cancer Res, 2008, 68(6), 1935-1944.

CAS Number

– 717907-75-0

Molecular Weight

– C21H20F3N7O3S

Compound Purity

– 0.9787

SMILES

– CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O

Pathway

– Cell Cycle/Checkpoint|||Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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