PERK-IN-3
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PERK-IN-3

SKU T12410-25 mg Category Brand:

Price range: 2,672 CAD through 4,480 CAD

Products Details

Product Description

– PERK-IN-3 is a potent inhibitor of PERK (IC50 of 7.4 nM).

Web ID

– T12410

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H16F2N4O2

References

– Axten JM , et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem. 2012 Aug 23;55(16):7193-207.

CAS Number

– 1337532-08-7

Molecular Weight

– C22H16F2N4O2

SMILES

– NC1=C2C(=COC2=NC=N1)C=3C=C4C(=CC3)N(C(CC5=C(F)C=CC(F)=C5)=O)CC4

Target

– Epigenetic Reader Domain|||Ligands for Target Protein for PROTAC

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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