PDK4-IN-1 hydrochloride

SKU T12412L-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 206 CAD through 4,752 CAD

Products Details

Product Description

– PDK4-IN-1 hydrochloride, an anthraquinone derivative, is a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4) with an IC50 value of 84 nM.

Web ID

– T12412L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H20ClN3O2

References

– Lee D, et al. Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases. J Med Chem. 2019 Jan 24;62(2):575-588.

CAS Number

– 2310262-11-2

Molecular Weight

– C22H20ClN3O2

Compound Purity

– 0.9967

SMILES

– Cl.O=C1c2ccccc2C(=O)c2c(cccc12)-c1cnn(c1)C1CCNCC1

Target

– YAP|||TAM Receptor|||Survivin

Pathway

– PI3K/Akt/mTOR signaling|||Apoptosis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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