PD173074
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PD173074

SKU T2642-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 1,102 CAD

Products Details

Product Description

– PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.

Web ID

– T2642

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H41N7O3

Citations

– 1. Huang G K, Huang C C, Kang C H, et al.Genetic Interference of FGFR3 Impedes Invasion of Upper Tract Urothelial Carcinoma Cells by Alleviating RAS/MAPK Signal Activity.International Journal of Molecular Sciences.2023, 24(2): 1776.

References

– Mohammadi M, et al. EMBO J, 1998, 17(20), 5896-5904.

CAS Number

– 219580-11-7

Molecular Weight

– C28H41N7O3

Compound Purity

– 0.9815

SMILES

– CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1

Pathway

– Tyrosine Kinase/Adaptors|||Apoptosis|||JAK/STAT signaling|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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