Products Details

Product Description

– PD-1/PD-L1-IN-28 (compound 3) is an immune checkpoint inhibitor of PD-1/PD-L1 signaling pathway (IC50=0.744 µM). PD-1/PD-L1-IN-28 shows good research potential in tumor immunity[1].

Web ID

– HY-148305

Shipping

– Room temperature

Molecular Formula

– C24H24N4O2

References

– [1]Jiang Sheng, et al. Preparation of phenyl substituted five membered heterocyclic compounds as immunocheckpoint inhibitors of PD-1 / PD-L1 signaling pathway. Patent WO2021031788A1.

CAS Number

– 2499965-07-8

Molecular Weight

– 400.47

SMILES

– OCCNCC1=CC=C(NC2=NN=C(C3=C(C)C(C4=CC=CC=C4)=CC=C3)O2)C=C1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– PD-1/PD-L1

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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