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Products Details
Product Description
– PD-1/PD-L1-IN-17 (Compound P20) is a potent inhibitor of PD-1/PD-L1 with an IC50 value of 26.8 nM. PD-1/PD-L1-IN-17 is a promising lead compound for the development of inhibitors of the PD-1/PD-L1 interaction. PD-1/PD-L1-IN-17 has the potential for the research of cancer diseases[1].
Web ID
– HY-144447
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H20ClN3O4
References
– [1]Huang X, et al. Design, synthesis, and structure-activity relationship of PD-1/PD-L1 inhibitors with a benzo[d]isoxazole scaffold. Bioorg Med Chem Lett. 2021 Nov 15;52:128403.
CAS Number
– 2851938-36-6
Molecular Weight
– 437.88
SMILES
– O=C([C@H](CO)NCC1=CC2=C(ON=C2NC3=CC=CC(C4=CC=CC=C4)=C3Cl)C=C1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PD-1/PD-L1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
