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Omeprazole-d3
$180 – $1,150
Products Details
Product Description
– Omeprazole-d3 is deuterium labeled Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].
Web ID
– HY-B0113S
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C17H16D3N3O3S
References
– [1]Li XQ, et al. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32(8):821-7.|[2]Jonkers D, et al. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J Antimicrob Chemother. 1996 Jan;37(1):145-50.
CAS Number
– 922731-01-9
Molecular Weight
– 348.43
Compound Purity
– 98.99
SMILES
– CC(C(OC)=C(C)C=N1)=C1CS(C2=NC3=CC=C(OC([2H])([2H])[2H])C=C3N2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Metabolic Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Autophagy;Bacterial;Proton Pump
Pathway
– Anti-infection;Autophagy;Membrane Transporter/Ion Channel
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
