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Ocaratuzumab
$350 – $1,450
Products Details
Product Description
– Ocaratuzumab (AME 133v) is an Fc-engineered humanized IgG1 anti-CD20 monoclonal antibody, with a Kd of ~100 pM. Ocaratuzumab exhibits more effective antibody-dependent cell-mediated cytotoxicity (ADCC)[1][2].
Web ID
– HY-P99308
Storage Temperature
– Store at -80°C for 2 years
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– N/A
References
– [1]Forero-Torres A, et, al. Results of a phase 1 study of AME-133v (LY2469298), an Fc-engineered humanized monoclonal anti-CD20 antibody, in FcγRIIIa-genotyped patients with previously treated follicular lymphoma. Clin Cancer Res. 2012 Mar 1;18(5):1395-403.|[2]Cheney CM, et, al. Ocaratuzumab, an Fc-engineered antibody demonstrates enhanced antibody-dependent cell-mediated cytotoxicity in chronic lymphocytic leukemia. MAbs. 2014 May-Jun;6(3):749-55.
CAS Number
– 1169956-08-4
Molecular Weight
– N/A
Compound Purity
– 95.00
SMILES
– [Ocaratuzumab]
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– H2O
Target
– CD20
Pathway
– Immunology/Inflammation
Product type
– Inhibitory Antibodies
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
