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Products Details
Product Description
– NSC89641 inhibits MERS-CoV Mpro, with an IC50 value < 3.5 μM. NSC89641 exhibits the high inhibitory potency against SARS-CoV-2 Mpro enzymatic activity, with an IC50 of 3.05 μM[1].
Web ID
– HY-155136
Shipping
– Room temperature
Molecular Formula
– C19H18N6O12
References
– [1]Chang YJ, et al. Combining virtual screening with cis-/trans-cleavage enzymatic assays effectively reveals broad-spectrum inhibitors that target the main proteases of SARS-CoV-2 and MERS-CoV. Antiviral Res. 2023 Aug;216:105653.
Molecular Weight
– 522.38
SMILES
– O=[N+]([O-])C1=CC([N+]([O-])=O)=CC=C1N[C@@H](CCC[C@H](C(O)=O)NC2=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C2)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
