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Products Details
Product Description
– NSC624206 is an inhibitor of ubiquitin E1 (UBA1), with an IC50 of ~9 μM. NSC624206 specifically blocks ubiquitin-thioester formation (IC50=13 μM) but has no effect on ubiquitin adenylation[1].
Web ID
– HY-103436
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H33Cl2NS2
References
– [1]Dana Ungermannova, et al. Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor. J Biomol Screen . 2012 Apr;17(4):421-34.
CAS Number
– 13116-77-3
Molecular Weight
– 410.51
SMILES
– CCCCCCCCCCNCCSSCC1=CC=C(Cl)C=C1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
