NLRP3-IN-8
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NLRP3-IN-8

SKU T62221-25 mg Category Brand:

Price range: 2,432 CAD through 4,000 CAD

Products Details

Product Description

– NLRP3-IN-8 (compound 27), an orally active NLRP3 inflammasome inhibitor, directly binds to its target with an IC50 of 1.23 μM for IL-1β inhibition. It demonstrates robust metabolic stability in liver microsomes (t1/2 = 138.63 min) and exhibits minimal toxicity (against L02: IC50 > 100 μM) [1].

Web ID

– T62221

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H20N2O6

CAS Number

– 2768650-56-0

Molecular Weight

– C23H20N2O6

SMILES

– C(=C/N(=O)=O)C1=C(/C=C/C2=CC=C(NC(=O)C3=CC=CO3)C=C2)C=C(OC)C=C1OC

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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