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NLRP3-IN-2
Price range: 50 CAD through 286 CAD
Products Details
Product Description
– NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.
Web ID
– T3230
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C16H17ClN2O4S
References
– Baldwin, A., Brough, D., & Freeman, S. (2015). Inhibiting the Inflammasome: A Chemical Perspective. Journal Of Medicinal Chemistry, 59(5), 1691-1710. doi: 10.1021/acs.jmedchem.5b01091
CAS Number
– 16673-34-0
Molecular Weight
– C16H17ClN2O4S
Compound Purity
– 0.9898
SMILES
– COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(N)(=O)=O
Target
– Others
Pathway
– Immunology/Inflammation|||NF-κB
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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