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N-Demethyl Mifepristone
SKU
HY-W740216-Get quote
Category Reference compound
Tags Drug Metabolite, Endocrinology, Glucocorticoid Receptor, Immunology/Inflammation, Metabolic Enzyme/Protease, Vitamin D Related/Nuclear Receptor
Size – Get quote
Products Details
Product Description
– N-Demethyl Mifepristone (RU 42633) is an active metabolite of Mifepristone (HY-13683). The affinities of N-Demethyl Mifepristone to the glucocorticoid receptor is 61% compared with 100% for Mifepristone[1].
Web ID
– HY-W740216
Shipping
– Room temperature
Molecular Formula
– C28H33NO2
References
– [1]Nguyen D, et al. Effects of Ketoconazole on the Pharmacokinetics of Mifepristone, a Competitive Glucocorticoid Receptor Antagonist, in Healthy Men. Adv Ther. 2017 Oct;34(10):2371-2385.
CAS Number
– 104004-96-8
Molecular Weight
– 415.57
SMILES
– C[C@@]12[C@](CC[C@@]2(O)C#CC)([H])[C@@]3([H])C([C@@H](C4=CC=C(C=C4)NC)C1)=C5C(CC3)=CC(CC5)=O
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite, Glucocorticoid Receptor
Pathway
– Immunology/Inflammation, Metabolic Enzyme/Protease, Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
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