ML-9
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ML-9

SKU T16104-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 557 CAD

Products Details

Product Description

– ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 causes autophagy by stimulating autophagosome formation and inhibiting their degradation.

Web ID

– T16104

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H18Cl2N2O2S

Citations

– 1. Sun L, Sun L, Li X, et al. A Novel Tigecycline Adjuvant ML-7 Reverses the Susceptibility of Tigecycline-Resistant Klebsiella pneumoniae. Frontiers in cellular and infection microbiology. 2022: 1341.

References

– Ito S, et al. ML-9, a myosin light chain kinase inhibitor, reduces intracellular Ca2+ concentration in guinea pig trachealis.Eur J Pharmacol. 2004 Feb 23;486(3):325-33.

CAS Number

– 105637-50-1

Molecular Weight

– C15H18Cl2N2O2S

Compound Purity

– 0.9969

SMILES

– Cl.Clc1cccc2c(cccc12)S(=O)(=O)N1CCCNCC1

Target

– Endogenous Metabolite|||DNA/RNA Synthesis

Pathway

– PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Membrane transporter/Ion channel|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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