MIV-247
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MIV-247

SKU T12051-1 mg Category Brand:

Price range: 2,192 CAD through 11,888 CAD

Products Details

Product Description

– MIV-247 is a selective and potent inhibitor of cathepsin S (Kis 2.1, 4.2, and 7.5 nM for human, mouse, and wild monkey cathepsin S, respectively), which attenuates mechanical anomalies in preclinical models of neuropathic pain, and can be used to study cardiac muscle injury.

Web ID

– T12051

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H24F3N3O4

References

– Hewitt E. et al. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358(3):387-96.

CAS Number

– 1352817-76-5

Molecular Weight

– C17H24F3N3O4

Compound Purity

– 0.9931

SMILES

– N(C([C@H](CC1(F)CCCC1)NC(C(C)(F)F)=O)=O)C2(C(C(N)=O)=O)CCC2

Target

– GABA Receptor|||Endogenous Metabolite

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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