Mcl1-IN-9

SKU T11977-25 mg Category Small Compound Brand: TargetMol

Price range: 2,672 CAD through 4,480 CAD

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Product Description

– Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) inhibitor, exhibiting an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.

Web ID

– T11977

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C37H39ClN4O4

References

– Lee T, et al, Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer. J Med Chem. 2019 Apr 25;62(8):3971-3988.

CAS Number

– 1810769-31-3

Molecular Weight

– C37H39ClN4O4

SMILES

– C(CCOC1=CC(C)=C(Cl)C(C)=C1)C=2C=3C(N4C2C(=O)N(CC5=CC(C(O)=O)=CC=C5)CCC4)=C(C=CC3)C=6C(C)=NN(C)C6C

Target

– Endogenous Metabolite

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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