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Products Details
Product Description
– Mca-SEVNLDAEFK(Dnp) is a peptide FRET substrate for Beta-secretase 1 (BACE-1), featuring the ‘Swedish’ Lys-Met/Asn-Leu mutation at the β-secretase cleavage site of the amyloid precursor protein (APP). Cleavage at the -Leu-Asp- site of Mca-SEVNLDAEFK(Dnp) releases the highly fluorescent 7-methoxycoumarin (Mca) fragment, which is freed from the quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher, leading to a significantly increased fluorescence intensity that is easily detectable.
Web ID
– T86868
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C68H88N14O27
CAS Number
– 1802078-31-4
Molecular Weight
– C68H88N14O27
SMILES
– C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCCNC2=C(N(=O)=O)C=C(N(=O)=O)C=C2)C(O)=O)=O)=O)CCC(O)=O)=O)C)=O)CC(O)=O)=O)CC(C)C)=O)CC(N)=O)=O)C(C)C)=O)CCC(O)=O)=O)CO)=O)C=3C=4C(=CC(OC)=CC4)OC(=O)C3
Product type
– Dye-Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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