Products Details

Product Description

– MAO-B-IN-5 is a potent, selective and orally active MAO-B inhibitor with an IC50 of 0.204 µM. MAO-B-IN-5 has the potential for the research of Parkinson’s disease (PD)[1].

Web ID

– HY-115986

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C19H21FN2O2

References

– [1]Wang Z,et al. Enhancing monoamine oxidase B inhibitory activity via chiral fluorination: Structure-activity relationship, biological evaluation, and molecular docking study. Eur J Med Chem. 2022; 228:114025.

CAS Number

– 849909-77-9

Molecular Weight

– 328.38

SMILES

– NC([C@@H]1CCCN1CC2=CC=C(C=C2)OCC3=CC(F)=CC=C3)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Monoamine Oxidase

Isoform

– MAO-A;MAO-B

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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