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Mal-Val-Ala-PABA-cGAMP
$1,050 – $4,650
Products Details
Product Description
– Mal-Val-Ala-PABA-cGAMP is a ADC linker that can be connected to a STING agonist. Mal-Val-Ala-PABA-cGAMP can be used for the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-148474
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C46H56N14O20P2
References
– [1]Peter Armstrong Thompson, et al. Composition of antibody construct-agonist conjugates and methods of use thereof. WO2017100305A2.
Molecular Weight
– 1186.97
Compound Purity
– 98.57
SMILES
– O=P(O)(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=C(NC3=O)N)O)O4)O[C@H]5[C@H]([C@@H](O[C@@H]5COP4(O)=O)N6C=NC7=C6N=CN=C7NC(OCC8=CC=C(NC([C@@H](NC([C@H](C(C)C)NC(CCCCCN9C(C=CC9=O)=O)=O)=O)C)=O)C=C8)=O)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
