LY2811376

SKU T2639-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 1,349 CAD

Products Details

Product Description

– LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including pepsin, cathepsin D, or renin.

Web ID

– T2639

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H14F2N4S

References

– May P, et al. J Neurosci, 2011, 31(46), 16507-16516.

CAS Number

– 1194044-20-6

Molecular Weight

– C15H14F2N4S

Compound Purity

– 0.9901

SMILES

– C[C@]1(CCSC(N)=N1)c1cc(c(F)cc1F)-c1cncnc1

Pathway

– Neuroscience

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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