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Lumiracoxib
Price range: 50 CAD through 112 CAD
Products Details
Product Description
– Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
Web ID
– T6574
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H13ClFNO2
Citations
– 1. Sun J, Zhang L, Zhang L, et al. A validated UHPLC–MS/MS method for simultaneous determination of lumiracoxib and its hydroxylation and acyl glucuronidation metabolites in rat plasma: Application to a pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis. 2021, 201: 114105.
2. Sun J, Zhang L, Zhang L, et al. A validated UHPLC-MS/MS method for simultaneous determination of lumiracoxib and its hydroxylation and acyl glucuronidation metabolites in rat plasma: application to a pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis. 2021: 114105.
3. Jiao W, Zhao X, Wu G, et al. Bioactivation of Lumiracoxib in Human Liver Microsomes: Formation of GSH‐and Amino Adducts Through Acyl Glucuronide. Drug Testing and Analysis. 2020, 12(6): 827-835.
References
– Esser R, et al. Br J Pharmacol, 2005, 144(4), 538-550.
CAS Number
– 220991-20-8
Molecular Weight
– C15H13ClFNO2
Compound Purity
– 0.9925
SMILES
– N(C1=C(CC(O)=O)C=C(C)C=C1)C2=C(Cl)C=CC=C2F
Pathway
– Immunology/Inflammation|||Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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