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Lu AF27139
Price range: 142 CAD through 1,856 CAD
Products Details
Product Description
– Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and rat, respectively). Lu AF27139 can be used in CNS diseases studies.
Web ID
– T9786
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H19ClF3N5O2S
References
– Hopper AT, et al. Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139. J Med Chem. 2021;64(8):4891-4902.
CAS Number
– 2097117-06-9
Molecular Weight
– C21H19ClF3N5O2S
Compound Purity
– 0.9975
SMILES
– FC(F)(F)c1nc(sc1C(=O)NC[C@@H](N1CCOCC1)c1ccc(Cl)cc1)-c1ncccn1
Pathway
– Membrane transporter/Ion channel|||Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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