Lometrexol disodium
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Lometrexol disodium

SKU T63240-25 mg Category Brand:

Price range: 3,680 CAD through 4,784 CAD

Products Details

Product Description

– Lometrexol (DDATHF) disodium is a potent inhibitor of human serine hydroxymethyltransferase 1/2 (hSHMT1/2) and antifolate, which reduces the activity of glycinamide ribonucleotide formyltransferase (GARFT) without causing detectable levels of DNA strand breaks. Lometrexol disodium exhibits anticancer effects by inhibiting the de novo synthesis of purines, causing abnormal cell proliferation, apoptosis and cell cycle arrest.

Web ID

– T63240

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H23N5Na2O6

CAS Number

– 120408-07-3

Molecular Weight

– C21H23N5Na2O6

SMILES

– [Na+].[Na+].Nc1nc2NC[C@H](CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)Cc2c(=O)[nH]1

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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