Download Files:
Levofloxacin (hydrate)
$66 – $92
Products Details
Product Description
– Levofloxacin hydrate (Levofloxacin hemihydrate) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrate inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrate can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrate shows anti-orthopoxvirus activity[1][2][3][4][5].
Web ID
– HY-B0330A
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C18H20FN3O4.1/2H2O
Citations
– Nat Commun. 2022 Mar 2;13(1):1116.|Antibiotics (Basel). 2022, 11(2), 192.|Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01921-20.|Clin Chem. 2019 Dec;65(12):1522-1531.
References
– [1]Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86.|[2]Pradeep, A.R., et al., Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial. J Investig Clin Dent, 2014.|[3]Lee, B.T., et al., Efficacy of Levofloxacin in the Treatment of BK Viremia: A Multicenter, Double-Blinded, Randomized, Placebo-Controlled Trial. Clin J Am Soc Nephrol, 2014.|[4]Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.|[5]Drlica K, et al. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92.
CAS Number
– 138199-71-0
Molecular Weight
– 370.38
Compound Purity
– 99.93
SMILES
– O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O.[0.5H2O]
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– DMSO : 8.33 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL
Target
– Antibiotic;Bacterial;DNA/RNA Synthesis;Orthopoxvirus;Topoisomerase
Isoform
– Topoisomerase
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
