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L 888607
SKU
HY-111271-10 mg
Category Reference compound
Tags GPCR/G Protein, Inflammation/Immunology; Endocrinology, Prostaglandin Receptor
$320 – $2,400
Products Details
Product Description
– L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1].
Web ID
– HY-111271
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H15ClFNO2S
References
– [1]Gervais FG, Identification of a potent and selective synthetic agonist at the CRTH2 receptor. Mol Pharmacol. 2005 Jun;67(6):1834-9.
CAS Number
– 860033-06-3
Molecular Weight
– 375.84
Compound Purity
– 99.95
SMILES
– O=C(O)C[C@@H]1CCN2C1=C(SC3=CC=C(Cl)C=C3)C4=C2C=C(F)C=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Endocrinology
Solubility
– DMSO : ≥ 150 mg/mL
Target
– Prostaglandin Receptor
Isoform
– DP;EP;FP;IP;TXA2/TP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.