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Product Description
– JQ1-FITC, a fluorescent BET bromodomain probe, exhibits high affinity binding to BRD4(BD1) and BRD4(BD2), with KD,app values of 6.5 nM and 5.8 nM respectively, as determined using GST-tagged BRD4 proteins in a CoraFluorTR-FRET assay; for BRD4(BD1), the value is 58.7 nM in a fluorescence anisotropy assay. It has excitation and emission maxima (λ) of 495 nm and 525 nm.
Web ID
– T83931
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C50H50ClN7O9S2.CF3CO2H
Molecular Weight
– C50H50ClN7O9S2.CF3CO2H
SMILES
– O=C(NCCCOCCOCCOCCCNC(NC1=CC=C(C(C(O)=O)=C1)C2=C(C(OC3=C2C=CC(O)=C3)=C4)C=CC4=O)=S)C[C@@H]5N=C(C6=CC=C(Cl)C=C6)C7=C(SC(C)=C7C)N8C5=NN=C8C.OC(C(F)(F)F)=O
Product type
– Dye-Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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