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JNJ-42165279
SKU
HY-19636-10 mg
Category Reference compound
Tags Autophagy;FAAH, Autophagy;Metabolic Enzyme/Protease;Neuronal Signaling, Neurological Disease
$100 – $620
Products Details
Product Description
– JNJ-42165279 is a FAAH inhibitor that inhibits hFAAH and rFAAH with IC50 of 70±8 nM and 313 ± 28 nM respectively.
Web ID
– HY-19636
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C18H17ClF2N4O3
References
– [1]Keith JM, et al. Preclinical Characterization of the FAAH Inhibitor JNJ-42165279. ACS Med Chem Lett. 2015 Nov 2;6(12):1204-8.
CAS Number
– 1346528-50-4
Molecular Weight
– 410.80
Compound Purity
– 99.87
SMILES
– O=C(N1CCN(CC2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=C(Cl)C=CN=C4
Clinical Information
– Phase 2
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Autophagy;FAAH
Pathway
– Autophagy;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.