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Products Details
Product Description
– Isoetharine (Isoetarine) is an orally active selective agonist of β-adrenergic receptors. Isoetharine is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].
Web ID
– HY-B1481A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H21NO3
References
– [1]Monika Maciag，et al. Evaluation of β-adrenergic ligands for development of pharmacological heart failure and transparency models in zebrafish. Toxicol Appl Pharmacol. 2022 Jan 1;434:115812.|[2]Katsuhisa Kurogi，et al. Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs. Biochem Pharmacol. 2012 Nov 1;84(9):1186-95.
CAS Number
– 530-08-5
Molecular Weight
– 239.31
SMILES
– OC1=CC=C(C(O)C(NC(C)C)CC)C=C1O
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Isoform
– β adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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