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IMR-1A
Price range: 70 CAD through 1,744 CAD
Products Details
Product Description
– IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
Web ID
– T3540
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H11NO5S2
Citations
– 1. Tang Y, Song H, Wang Z, et al. Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations. Cell Reports. 2022, 39(2): 110622
2. Tang Y, Song H, Wang Z, et al.Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations.Cell Reports.2022, 39(2): 110622.
References
– Astudillo L,et al. The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis. Cancer Res. 2016 Jun 15;76(12):3593-603.
CAS Number
– 331862-41-0
Molecular Weight
– C13H11NO5S2
Compound Purity
– 0.971
SMILES
– COc1cc(C=C2SC(=S)NC2=O)ccc1OCC(O)=O
Target
– Others
Pathway
– Metabolism|||Proteases/Proteasome|||Neuroscience|||Stem Cells
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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